In Newcastle upon Tyne, England, 10-year-old Mary Bell becomes a murderer after she strangles a 4-year-old boy to death on May 25, 1968, just one day before her 11th birthday. Two months later, at age 11, Bell murders another little boy. In Fayette County, Georgia, troubled teen lovers Holly Harvey and Sandra Ketchum are forbidden from seeing one another by Holly's grandparents. Holly resents her grandparents and their strict rules, and with the help of Sandra, the two teens decide to murder the elderly couple by stabbing them to death. And in Gary, Indiana, 15-year-old Paula Cooper and her friends need some quick cash so they decide to rob 78-year-old Bible teacher Ruth Pelke under the pretense of asking for Bible lessons. Upon allowing the girls into her home, Ruth Pelke is brutally stabbed to death by the ringleader of the clique, Paula Cooper.
In 1934, Eva Coo and Martha Clift drove Henry Wright, a fellow employee, to an isolated location in Oneonta, New York. There, Eva bludgeoned him with a mallet and Martha ran over him with a car. Coo and Clift's motive for murder was simply to collect the life insurance that had been purchased on Wright. In Texas, Celeste Beard conspires to murder her husband, a retired television executive and self-made multi-millionaire, with her lesbian lover Tracey Tarlton. And in 19th century Australia, baby farmer Sarah Makin murders innocent infants while collecting money from the children's mothers.
Nurse Jane Toppan murders at least 31 of her patients in a sadistic fashion, Dana Sue Gray kills three women and severely injures another due to a crave for power, thirst for cash and hatred of her mother. And in Florida, an unstable babysitter named Christine Falling betrays parents' trust by suffocating the children that she was supposed to protect.
"J.R", age 12, and her 23-year-old boyfriend brutally slaughter her parents and brother so they can be together, Sharee Miller uses the Internet as a tool to manipulate her lover into killing her husband, and Kristin Rossum murdered her husband to hide her affair with her boss and addiction to crystal meth.
Winnie Ruth Judd impulsively murders her friends after fighting over a man and has them cut up with the intention of dumping their remains in the Pacific Ocean. Carolyn Warmus was so desperate for a man's love that she shot his wife nine times. Daphne Wright butchered another deaf woman to protect the only love she had ever known.
In mid-1960s England, Myra Hindley and her sadistic boyfriend Ian Brady go on a sick, murderous rampage that takes the lives of five children, burying their victims in the couple's favorite place - the English moors. In August 1969, Susan Atkins, Patricia Krenwinkel and Leslie Van Houten slaughtered seven prominent people, including pregnant actress Sharon Tate, in the Hollywood hills. All three girls were disciples of infamous cult leader Charles Manson. Tania Herman was so under the spell of her lover Joe Korp, that she willingly killed her lover's wife simply because he asked her.
Compulsive liar Lisa M. Montgomery's supposed pregnancy was a fraud, and to avoid being exposed, she murdered a pregnant woman in cold blood so she could steal her unborn baby. Best friends Pauline Parker and Juliet Hulme were so obsessed with each other and their fantasy world, they killed a loving mother to protect their friendship. Catherine Birnie was hopelessly in love with a sexually sadistic serial killer and became one herself.
For almost three decades, Rosemary West and her husband rape, torture and murder at least 11 women before burying them under their backyard. Martha Beck helps her con artist boyfriend trick women, and three lives (two women and a toddler) are cut short as a result. Erika Sifrit goes to Ocean City with her husband, giving an innocent couple an invitation back to their condo to be murdered.
Waneta Hoyt kills her babies and blames Sudden Infant Death Syndrome (aka SIDS) for the deaths to gain sympathy from other people. Driven by a deadly delusion, Andrea Yates drowns her five children one by one to save their souls. Susan Smith outrages America by sending her two young boys to a watery grave in order to earn back her lover.
In 1965 Indianapolis, Gertrude Baniszewski tortured and murdered sixteen year-old Sylvia Likens and got her children to help do the dirty work. Antoinette Frank was a killer cop who shot a fellow officer and two owners of a Vietnamese restaurant she helped guard at nighttime. And Sharon Kinne traded her life as a suburban mom for a life of crime and still may be among us today.
At age sixteen, Sarah Marie Johnson shot both of her parents because they wouldn't let her see her nineteen-year-old boyfriend. Piper Rountree wouldn't rest until her ex-husband was in the grave for leaving her. Devil worshiping Christa Pike, convinced that college classmate Colleen Slemmer was trying to steal her boyfriend, cut Colleen over 300 times and bludgeoned her with a rock before taking a piece of the skull as a trophy.
Barbara Opel talked children (including her own daughter) into brutally murdering a helpless old man who generously helped them during trying times. Out in the Wild West, Kate Bender was prepared to help her family of serial killers. Sante Kimes led her son into a life of crime, and they left a trail of frauds, scams, bills, and bodies behind them.